The Milton Hershey School in December denied a 13-year-old boy admission because of his HIV positive status.
The school said they had the legal right to do so.
Tuesday, the AIDS Healthcare Foundation spoke out against the decision, calling it unacceptable discrimination.
The group spent nearly an hour protesting, chanting, and shouting in front of the Hershey Company's headquarters off Hersheypark Drive in Derry Township.
Although the Hershey Company is legally separate from the Milton Hershey School and has no say about who gets into the school, protestors want the company to speak out against the school.
"Milton Hershey left a trust to the Hershey Company, and even though they aren't directly involved with their decision making we feel it is their job to step in and denounce this type of discrimination," said Jessica Reinhart, who was protesting.
Across town, the campus of the Milton Hershey School was quiet. A spokeswoman there said the decision was made to protect other students.
"We did what we think is best for our children, the children in our care," said Connie McNamara.
She is hoping the public will consider both sides of the issue.
"We understand there are differences of opinion on this issues, but we hope fair-minded people also understand we had to weight a lot of complicated factors. This wasn't a decision made out of ignorance," she said.
McNamara added the school is prepared for the issue to be heard in court.